• Users Online: 63
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2019  |  Volume : 31  |  Issue : 3  |  Page : 206-211

Comparison of topographic indices and corneal higher order aberrations in eyes with an extreme asymmetry of keratoconus with control eyes

1 Department of Refractive Surgery, C. H. Nagri Eye Hospital, Ahmedabad, Gujarat, India
2 Department of Ophthalmology, AMC MET Medical College, Ahmedabad, Gujarat, India

Correspondence Address:
Dr. Shwetambari G Singh
Department of Refractive Surgery, C. H. Nagri Eye Hospital, Ellisbridge, Ahmedabad - 380 006, Gujarat
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/kjo.kjo_76_19

Rights and Permissions

Purpose: To compare topographic indices and anterior corneal higher order aberrations (HOAs) of forme fruste keratoconus (KC) (fellow eyes) with clinical KC and control eyes. Setting: Tertiary Eye Hospital, India. Materials and Methods: This study retrospectively reviewed 298 patients with KC. Patients were evaluated with placido-based topographer. KC was diagnosed according to Rabinowitz and McDonnell criteria and clinical sign. Twenty-one patients with clinical KC in one eye (Group A), fellow eye (Group B) with normal topography with no clinical sign, and 21 control eyes (Group C) were included in the study. Topographic indices (keratometry, inferior superior ratio, irregularity, shape factor, and eccentricity) and HOAs (trefoil, coma, spherical aberration, total root mean square [RMS], HOAs RMS of third to seventh order for 6 mm diameter) were obtained. Group B was compared with Groups A and C. Results: The prevalence of an extreme asymmetry of KC in our study population is 7.04% with mean age of 21.98 ± 7.39 years. All topographic indices were higher in Group A compared to Group B (P < 0.01) and no significant difference was found between Groups B and C. All HOAs were higher in Group A compared to Group B (P < 0.05). HOAs RMS, oblique trefoil and spherical aberration were significantly higher in Group B compared to Group C (P < 0.02). Of these 21 patients, four had severe to advanced KC in one eye. Conclusions: Corneal HOAs changes are first to appear in fellow eyes of unilateral KC, which may makes them useful tool in monitoring progression and early detection of KC changes in fellow eyes.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded240    
    Comments [Add]    
    Cited by others 1    

Recommend this journal