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Year : 2021  |  Volume : 33  |  Issue : 2  |  Page : 205-208

Challenges in the diagnosis of early endogenous fungal endophthalmitis

Department of Uvea and Viteoretinal Services, Dr. Tony Fernandez Eye Hospital, Aluva, Kerala, India

Correspondence Address:
Dr. Nusrath Parambil
Dr. Tony Fernandez Eye Hospital, Aluva - 683 101, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/kjo.kjo_87_20

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Endogenous fungal endophthalmitis (EFE) is an uncommon disease caused by the dissemination of fungal infection to posterior segments of the eye and has a high rate of visual loss. Most patients have associated predisposing risk factors, including immunocompromised conditions, and the condition is less likely to occur in healthy individuals. Here, we report two patients who presented like uveitis and deteriorated after starting standard treatment for uveitis, which included steroids. They were later diagnosed with EFE. Fungal endophthalmitis should be suspected even in ambulatory individuals with immunocompromised states, when they present with uveitis like features, before starting steroid treatment. Polymerase chain reaction based diagnosis is extremely useful and should be considered in diagnosing EFE.

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