• Users Online: 160
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
CASE REPORT
Year : 2021  |  Volume : 33  |  Issue : 3  |  Page : 344-348

Long-term linezolid: Unnerving the nerves?


Department of Ophthalmology, MGM Institute of Health Sciences, Navi Mumbai, Maharashtra, India

Correspondence Address:
Dr. Sayali Santosh Amberkar
New PG Hostel, MGM Institute of Health Sciences, Navi Mumbai - 410 209, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/kjo.kjo_110_20

Rights and Permissions

It is well documented that systemic antimicrobials can cause ocular side effects. This becomes especially relevant in multidrug therapy where more than one drug can cause similar ocular side effect. We describe a case of progressive decrease in vision associated with linezolid therapy in a 17-year-old female patient, on treatment with the second-line anti-tuberculous drugs including linezolid, for multiple drug-resistant tuberculosis presented to us with painless progressive decrease in vision in both eyes. Color vision was defective and fundus examination revealed optic disc edema in both eyes. Since the patient was not on ethambutol and gave a history of peripheral neuropathy, linezolid-induced toxic optic neuropathy was suspected and linezolid dechallenge was done. Discontinuation of linezolid treatment resulted in marked improvement in visual acuity. Our report emphasizes the need for early detection of ocular side effects and how monitoring of visual function is imperative in patients on long-term linezolid treatment.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed122    
    Printed0    
    Emailed0    
    PDF Downloaded12    
    Comments [Add]    

Recommend this journal