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  Indian J Med Microbiol
 

Figure 1: (a)Stage 1 consisting in demarcation line is seen as whitish line located between the normally vascularized retina and the peripheral avascular retina. This stage resolves spontaneously without progression. (b) Stage 2 consisting in visible ridge at demarcation line with height and width without blood vessel growth towards vitreous. This stage carefully requires only observation by trained ophthalmologist. (c) Stage 3 characterized by severely abnormal blood vessel growth toward the central vitreous; when this stage is associated with Plus Disease (enlarged and twisted blood vessels emerging from optic nerve) it can lead to retinal detachment so treatment with infrared laser photocoagulation (or Anti VEGF intraocular injections) should be performed within the next 48 hours after diagnosis is made. (d) Stage 4A Partially retinal detachment not involving foveal area. Vitreoretinal surgery or scleral buckling may be indicated. (e) Partially retinal detachment involving macular area. Vitreoretinal surgery may be indicated. 1F Total retinal detachment. Surgical treatment almost always does not provide any visual acuity improvement.

Figure 1: (a)Stage 1 consisting in demarcation line is seen as whitish line located between the normally vascularized retina and the peripheral avascular retina. This stage resolves spontaneously without progression. (b) Stage 2 consisting in visible ridge at demarcation line with height and width without blood vessel growth towards vitreous. This stage carefully requires only observation by trained ophthalmologist. (c) Stage 3 characterized by severely abnormal blood vessel growth toward the central vitreous; when this stage is associated with Plus Disease (enlarged and twisted blood vessels emerging from optic nerve) it can lead to retinal detachment so treatment with infrared laser photocoagulation (or Anti VEGF intraocular injections) should be performed within the next 48 hours after diagnosis is made. (d) Stage 4A Partially retinal detachment not involving foveal area. Vitreoretinal surgery or scleral buckling may be indicated. (e) Partially retinal detachment involving macular area. Vitreoretinal surgery may be indicated. 1F Total retinal detachment. Surgical treatment almost always does not provide any visual acuity improvement.